Walk into Eybna’s headquarters outside Tel Aviv and you don’t just smell terpenes—you feel the hum of a company trying to redesign how natural molecules interact with the human body. Screens glow with receptor maps, simulations, and EEG data. Somewhere between biotech precision and cannabis culture, Eybna is building a future where plant molecules replace some of the world’s most harmful habits.
“From day one it wasn’t only about cannabis,” says VP of Sales Avichai Elbaz. “It was about understanding how natural molecules affect us—and using data science to break apart the entourage effect.”
From Israel’s Cannabis Legacy to Global Wellness
Founded in 2015 in partnership with Seach—one of Israel’s earliest licensed medical cannabis operators—Eybna began by restoring the aromatic complexity lost during cannabis extraction. But the mission quickly expanded. Terpenes weren’t just flavor; they were bioactive compounds capable of interacting with GABA, serotonin, dopamine, and endocannabinoid receptors.
Today the company has about 70 employees across Israel, California, and Berlin, supplying terpene formulations to cannabis brands worldwide while quietly building a research engine aimed at something bigger: botanical wellness beyond cannabis.
Terpenes as Function, Not Fragrance
Eybna’s research blends four layers of insight into one system. The team draws from existing essential-oil literature, computational simulations using NVIDIA-powered supercomputing, laboratory receptor testing on human-derived cells, and early-stage human studies that sometimes include EEG readings to measure brainwave changes.
The outcome is Eybna’s Receptor-Specific™ line—functional terpene formulations tuned for sleep, relaxation, mood, focus, or inflammation. Instead of strain names, these blends are built around receptor pathways and biological outcomes.
“It’s trillions of possible combinations,” Tom Maor, EU sales explains. “That’s why we work with full formulations of many molecules rather than chasing a single ‘hero’ compound.”
BUUZ®: A Social “Buzz” Without the Alcohol
One of Eybna’s most intriguing innovations isn’t a vape—it’s a drink ingredient. In partnership with Gat Foods/Coca-Cola Israel, the company developed a terpene formulation designed to reproduce the light, social uplift of alcohol by targeting GABA receptors, but without ethanol, hangovers, or calories.
In a double-blind study of 240 participants, the active formula produced noticeable improvements in sociability and mood. At MJBizCon, Eybna’s mocktail bar gave attendees a clear-headed, functional “buzz” that hinted at a new category of social beverages.
This direction reveals the company’s long-term intent: replacing harmful habits with validated plant-based alternatives.
A Global View of Cannabis Culture
Because Eybna operates in Israel, the U.S., and Europe, the team has a front-row seat to emerging shifts. American consumers chase high THC and infused pre-rolls; Europeans lean into hash culture and deeper aroma profiles; German medical markets now list terpene data on product labels.
Yet the most consistent trend across all markets is the rise of effect-based products. Consumers may not always know the underlying chemistry, but they increasingly want to understand how a product will make them feel—calmer, more focused, more creative, or better prepared for sleep.
“People don’t always know the science,” Gil Onn from the Marketing department. “But they know how they want to feel.”
The Long Game: A New Wellness Paradigm
Eybna’s ambitions extend well beyond cannabis culture. The company is manufacturing terpene-infused alternatives to tobacco and alcohol, functional ingredients for beverage and food brands, and botanical formulations that may one day rival certain pharmaceutical solutions.
“Eybna is accelerating the world's transition to Safe, Longevity-Promoting Botanical Neuromodulators and Wellness Products,” Nadav says, “We believe that in a few years people will enjoy a new age of Wellness products that will modulate our brain and body performance, help improving our quality of life safely and eventually offer an absolute replacement to Alcohol, Tobacco, and Pharmaceuticals.”
If they succeed, the entourage effect won’t just describe cannabis—it will describe a new era of botanical intelligence, where plant compounds are mapped, understood, and harnessed with scientific precision to support clearer, calmer, healthier lives.
